Tag: Thomson Lab

  • A science trailblazer retires: Stem cell researcher James Thomson’s legacy changed the future of biology

    James Thomson helped the scientific world turn its attention to the remarkable stem cells that give rise to all of the building blocks of life. After more than 30 years with UW–Madison and 15 years with the Morgridge Institute, Thomson has announced plans to retire in July 2022.

  • Human developmental clock mimicked in a dish

    A Morgridge regenerative biology team has created a first-ever human model for developmental timing: A “clock in a dish” that will help explore mysteries of early human development.

  • Stem cell scientists clear another hurdle in creating transplant arteries

    Scientists at the Morgridge Institute are working toward a dream of creating artery banks with readily-available material to replace diseased arteries during surgery. Recent work highlights highlights a better way to grow smooth muscle cells, putting the science one step closer to that goal.

  • Fujifilm Cellular Dynamics’ $21 million plant is significant for regenerative medicine

    via BizTimes

    A new Madison stem cell manufacturing plant could have a significant impact on the Wisconsin medical landscape and the field of regenerative medicine, along with the local economy.

  • Stem cells: Where are we going?

    Together with the University of Wisconsin–Madison, we look back on 20 years of stem cell research and see where we’re going next. Catch up on what’s happened since James Thomson’s prescient prediction that stem cells “will change medicine, period.”

  • Collaboration leads to ‘dream’ of artery bank

    Just as blood banks are essential to medicine, the Thomson Lab hopes to see the advent of artery banks that give surgeons a better, readily available material to replace diseased arteries. The lab is using pluripotent stem cells to grow the cellular building blocks of the artery — endothelial and smooth muscle cells — and coax them into assembling into arteries that can grow and thrive in a majority of patients.

  • Out of left field: Thomson looks at discovery and the future of science

    James Thomson, the UW–Madison biologist whose stem cell discovery 20 years ago opened fascinating and promising new avenues in science, took time to discuss his thoughts on the breakthrough and what the future holds for the field of regenerative medicine.

  • New stem cell method sheds light on a tell-tale sign of heart disease

    While refining ways to grow arterial endothelial cells in the lab, a regenerative biology team at the Morgridge Institute for Research unexpectedly unearthed a powerful new model for studying a hallmark of vascular disease.

  • Stem cell advance brings bioengineered arteries closer to reality

    New techniques developed at the Morgridge Institute for Research and the University of Wisconsin–Madison have produced, for the first time, functional arterial cells at both the quality and scale to be relevant for disease modeling and clinical application.

  • Can artery ‘banks’ transform vascular medicine?

    The prospect of creating artery “banks” available for cardiovascular surgery, bypassing the need to harvest vessels from the patient, could transform treatment of many common heart and vascular ailments.

  • Thomson honored for stem cell research legacy

    Wisconsin biotechnology advocacy organization BioForward honored two giants in state biomedical innovation — stem cell research pioneer James Thomson and entrepreneur Ralph Kauten — for their scientific and business achievement during its annual summit September 27 in Madison.

  • Stem cells help predict neural toxicity

    A new system developed by scientists at the Morgridge Institute for Research and the University of Wisconsin–Madison may provide a faster, cheaper and more biologically relevant way to screen drugs and chemicals that could harm the developing brain.

  • James Thomson: Opening access to the cellular building blocks of life

    Thomson’s discoveries in human stem cell research at UW–Madison have redefined biomedicine, first with the isolation and culturing of human embryonic stem cells in 1998; then in the development of human pluripotent stem cells from adult skin cells in 2007.

  • A shift in stem cell research

    A team of engineers at the University of Wisconsin–Madison has created a process to improve the creation of synthetic neural stem cells for use in central nervous system research.

  • Thomson lab lands $2.2 million NIH grant

    With a $2.2 million grant from the National Institutes of Health, stem cell pioneer Dr. James Thomson, University of Wisconsin–Madison associate professor of biomedical engineering William Murphy and School of Medicine and Public Health medical informatics professor David Page will lead a team to derive and assemble the distinct cell types found in the human cerebral cortex.

  • Study shows patient’s own cells may hold therapeutic promise after reprogramming, gene correction

    Scientists from the Morgridge Institute for Research, the University of Wisconsin–Madison, the University of California and the WiCell Research Institute moved gene therapy one step closer to clinical reality by determining that the process of correcting a genetic defect does not substantially increase the number of potentially cancer-causing mutations in induced pluripotent stem cells.

  • Wisconsin, Morgridge scientists excise vector, exotic genes from induced stem cells

    A team of scientists from the Morgridge Institute for Research at the University of Wisconsin–Madison reports that it has created induced human pluripotent stem (iPS) cells completely free of viral vectors and exotic genes.

  • Stem cell pioneer James Thomson to steer regenerative medicine at MIR

    The Morgridge Institute for Research, the private, not-for-profit side of the Wisconsin Institutes for Discovery, is announcing the appointment of world-renowned stem cell pioneer and researcher James Thomson as the first member of its multidisciplinary scientific leadership team.